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Fournier's Gangrene In Females

The following risk factors are associated with Fourniers gangrene in women. It is more likely to occur in diabetics alcoholics or those who are immunocompromised.


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Median number of debridements for females was 2 13.

Fournier's gangrene in females. Typically very rare and affecting only males necrotizing fasciitis is occurring at much higher rates in both men and women taking diabetes drugs. It most often occurs in men however with anyone suffering diabetes alcoholism kidney problems steroid use or immune system deficiencies most at risk. It is a true urological emergency due to the high mortality rate but fortunately the condition is rare.

Though women rarely develop Fourniers gangrene destruction usually occurs in the fibrous tissue that makes up the vaginal wall buttocks abdominal wall back pelvis and retroperitoneum. The FDA diabetes drug infection warning was prompted by 12 cases of Fourniers gangrene in the past five years in both men and women taking glucose-regulating diabetes drugs. Among these twelve documented cases of diabetes patients developing necrotizing fasciitis from SGLT2 inhibitors each has required surgery many have been left.

Fournier gangrene is necrotizing fasciitis of the perineum. Clearly it can no longer by considered idiopathic in its origin as most infection can be localized to a cutaneous urethral or rectal source. Mortality rate during initial admission was 6 for females.

It was first described by. Fournier gangrene is a form of necrotising fasciitis gangrene that can affect the vulva andor perineum in women. Fourniers gangrene is an aggressive disease affecting the perineum.

Bladder infections are the next most likely cause. Insect bites burns trauma and circumcision have been reported as causes of pediatric Fournier gangrene which is rarely seen 1. Fourniers gangrene FG is a rare and potentially life-threatening surgical condition.

It is defined as a necrotizing infection of the perineal genital or anorectal region. A pus-producing bacterial infection abscess in the vaginal area. It is primarily a clinical diagnosis and definitive treatment must not be delayed to perform imaging which usually has an ancillary role 9.

The skin along with the superficial and fibrous membranes that divide the muscles and protect nerves and vessels around the genital region are often damaged. In women Fournier gangrene acts more like necrotizing fasciitis because of the thicker subcutaneous layers involving the labia majora and the perineum. About one per 62500 males are affected per year.

Urinary tract infections are the most common root cause of Fournier gangrene. It presents in a broad age range and can have an indolent onset thus requiring a high. In women most cases of Fournier gangrene follow a hysterectomy and are more likely to occur where conditions are unsanitary.

Since 1950 more than 1800 cases for study have been reported in English language medical literature. Fourniers gangrene in women The majority of people who develop Fourniers gangrene are male but the infection can happen in women. Fourniers gangrene is an extremely rare but life-threatening bacterial infection of the tissue under the skin that surrounds muscles nerves fat and blood vessels of the perineum.

Males are affected about 40 times more often than females. 1 Immediate broad spectrum antibiotics and debridement are essential in management. Fourniers gangrene involves an infection in the scrotum which includes the testicles penis or perineum.

It commonly occurs in older men but it can also occur in women and children. This truly emergent condition is typically seen in elderly diabetic or otherwise immune-compromised individuals. Fournier gangrene is usually secondary to perirectal or periurethral infections associated with local trauma operative procedures or urinary tract disease.

The resulting infection withholds oxygen from the affected tissue leading to necrosis. Female patients had a higher median BMI than males 421 vs 337 respectively. In women additional causes of Fournier gangrene have included septic abortion Bartholin gland or vulvar abscess episiotomy and hysterectomy 9.

The perineum is the area between the scrotum. Necrotizing fasciitis also known as Fourniers gangrene is a flesh-eating bacterial infection affecting the genital area that results in permanent disfigurement and life-threatening side effects. Fournier gangrene is a type of necrotizing fasciitis or gangrene affecting the external genitalia or perineum.

Fourniers gangrene affects the genitals or the urinary tract often beginning when bacteria enters through a wound. Fournier gangrene is usually the result of another infection in or near the genitals. Fourniers gangrene is a rare and often fulminant necrotizing fasciitis of the perineum and genital region frequently due to a synergistic polymicrobial infection.

The most common anatomic region of gangrene involvement in females was labia 76 followed by perineum 55 and gluteusbuttocks 42.


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